PO-0857 MRI-derived radiomics to select patients with high-risk prostate cancer for adjuvant radiotherapy

Discovery Radiomics for Multi-Parametric MRI Prostate Cancer Detection

Prostate cancer is the most diagnosed form of cancer in Canadian men, and is the third leading cause of cancer death. Despite these statistics, prognosis is relatively good with a sufficiently early diagnosis, making fast and reliable prostate cancer detection crucial. As imaging-based prostate cancer screening, such as magnetic resonance imaging (MRI), requires an experienced medical professio...

adjuVaNt chemOtherapy iN high-risk prOstate caNcer

In the RTOG 0521 study, patients with localized, nonmetastatic, high-risk prostate cancer were randomized to androgen suppression (AS) + radiotherapy (RT) vs AS+RT followed by chemotherapy (CT) with docetaxel and prednisone. High-risk prostate cancer categories were defined as: 1) Gleason (GL) 7–8, any T-stage, and prostate-specific antigen (PSA) ≥20, or 2) GL 8, ≥T2, any PSA, or 3) GL 9–10, an...

Point: Early Salvage vs Adjuvant Radiotherapy for High-Risk Prostate Cancer.

By definition, adjuvant oncologic therapy refers to the postsurgical treatment of patients who are at high risk for recurrence but lack measurable disease. Adjuvant radiotherapy is considered a standard of care in a number of cancer types, including tumors of the breast, brain, head and neck, stomach, rectum, cervix, and endometrium, among others. In these cases, adjuvant radiation has been dem...

Combined brachytherapy and external beam radiotherapy without adjuvant androgen deprivation therapy for high-risk prostate cancer

BACKGROUND To report the outcomes of patients treated with combined iodine-125 (I-125) brachytherapy and external beam radiotherapy (EBRT) for high-risk prostate cancer. METHODS Between 2003 and 2009, I-125 permanent prostate brachytherapy plus EBRT was performed for 206 patients with high-risk prostate cancer. High-risk patients had prostate-specific antigen ≥ 20 ng/mL, and/or Gleason score ...

Point: Early Salvage vs Adjuvant Radiotherapy for High-Risk Prostate Cancer. - PubMed - NCBI